Figure 7.

The effects of macrophage depletion with platelet-activating factor acetylhydrolase (PAF-AH). A and B. Show collagen staining (blue) in the lungs of rats with heart failure (HF) treated with vehicle (VEH) or with HF treated with PAF-AH (7 days), respectively. C. PAF-AH treatment attenuated HF-induced edema formation, as indicated by decreased wet-to-dry weight ratio. D. TNF-α levels in the lung were not significantly altered after treatment with PAF-AH in the HF group compared to VEH treated HF group. *, P<0.05, n=6 (HF + VEH) and n=6 (PAF-AH) treated group.