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. 2020 Sep 7;26(33):4945–4959. doi: 10.3748/wjg.v26.i33.4945

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©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.

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Chemical structures of resveratrol and 5-aminosalicylic acid, and timeline of in vivo experiment. A: The chemical structures of resveratrol; B: The chemical structures of 5-aminosalicylic acid; and C: Timeline of in vivo experiment. Dextran sulfate sodium (DSS) group was induced by two cycles of intake of drinking water containing 3% DSS for 7 d and normal drinking water for 7 d. Other groups were also treated by two cycles, first received DSS by drinking water for 7 d, followed by treatment of 5-aminosalicylic acid or resveratrol by gavage for 7 d. DSS: Dextran sulfate sodium; 5-ASA: 5-aminosalicylic acid; RES: Resveratrol.