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. 2020 Sep 7;26(33):4945–4959. doi: 10.3748/wjg.v26.i33.4945

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©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.

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Structures of the intestinal epithelial cells and autolysosomes observed by transmission electron microscopy. A: Control group showed normal organelle structure; B: Dextran sulfate sodium induced colitis group showed mitochondrial swelling and ruptures of internal cristae, along with distention of the rough endoplasmic reticulum; C: 5-aminosalicylic acid group revealed that mitochondrial swelling was not obvious, and mitochondrial cristae showed blurred appearance; and D: Resveratrol treatment group showed that organelle structure was basically normal, and autophagosome could be observed. ER: Endoplasmic reticulum, M: Mitochondria.