Table 1.
Baseline characteristics of the patients, n (%)
| Variable | All patients (n = 60) |
| Age (yr) | 74.0 (68.5–79.8) |
| Female | 47 (78.3) |
| Menopause | 47 (100) |
| BMI (kg/m2) | 21.0 (19.2–23.6) |
| Etiology | |
| HBV/HCV/PBC/Others | 10/25/19/6 |
| Liver cirrhosis | 25 (41.7) |
| Child-Pugh A/B | 21/4 |
| Child-Pugh score | 5 (5–6) |
| MELD score | 3.0 (0.5–6.0) |
| Osteoporotic fracture | 25 (41.7) |
| AST (U/L) | 26 (20–28) |
| ALT (U/L) | 15 (12–24) |
| ALP (U/L) | 283 (235–332) |
| GGT (U/L) | 24 (17–40) |
| Total bilirubin (mg/dL) | 0.7 (0.5–0.9) |
| Platelet (× 104/μL) | 16.6 (12.6–22.7) |
| Prothrombin time | 98 (86–100) |
| Albumin (g/dL) | 4.1 (3.9–4.4) |
| Creatinine (mg/dL) | 0.7 (0.6–0.9) |
| eGFR (mL/min/1.73 m2) | 64 (53–75) |
| Ca (mg/dL) | 9.4 (9.1–9.7) |
| Pentosidine (μg/mL) | 0.0584 (0.0475–0.0761) |
| TRACP-5b (mU/dL) | 533 (358–661) |
| Total P1NP (ng/mL) | 57 (44-80) |
| Lumbar spine BMD (g/cm2) | 0.84 (0.76–0.94) |
| Lumbar spine T score | -2.41 (-1.28)–(-2.94) |
| Femoral neck BMD (g/cm2) | 0.61 (0.56–0.66) |
| Femoral neck T score | -2.94 (-2.64)–(-3.32) |
| Total hip BMD (g/cm2) | 0.67 (0.59–0.71) |
| Total hip T score | -2.48 (-2.07)–(-2.95) |
Data are expressed as median (interquartile range) or number (percentage). Othrers (alcoholic liver disease, n = 4; autoimmune hepatitis, n = 1; nonalcoholic steatohepatitis, n = 1). ALP: Alkaline phosphatase; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; BMD: Bone mineral density; BMI: Body mass index; BP: Bisphosphonate; HBV: Hepatitis B virus; HCV: Hepatitis C virus; Egfr: Estimated glomerular filtration rate; GGT: Gamma-glutamyltransferase; MELD: Model for end-stage liver disease; P1NP: Procollagen type N-terminal propeptide; TRACP-5b: Tartrate-resistant acid phosphatase 5b; PBC: Primary biliary cholangitis.