Figure 1.

Spatiotemporal Expression of Adamts18 mRNAs in Mouse Lungs

(A) Upper panels: Cartoon picture illustrates the spatiotemporal expression pattern of Adamts18 mRNAs at different stages of lung development in mice. Lower panels: In situ hybridization (ISH) of Adamts18 mRNA in wild-type mouse lungs (consecutive transverse sections of lung tissue). ISH-positive signals are shown as pink dots in cells (red arrows). Scale bar, 50 μm.

(B) qRT-PCR analysis of Adamts18 mRNA from E11.5 to 16-month-old mouse lungs (n = 3/time point). The relative quantity of Adamts18 mRNA was normalized to that of the housekeeping gene Gapdh using the ΔΔCt method. Data are expressed as mean ± SEM.

See also Table S5.