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. 2020 Aug 24;11:2048. doi: 10.3389/fmicb.2020.02048

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Copyright © 2020 Wambui, Cernela, Corti and Stephan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Antimicrobial activity of C. gasigenes CGAS001 crude polyketide extract. (A) The potential of CGAS001 to synthesize antimicrobial compounds was initially identified using the agar streak method whereby the growth of Listeria monocytogenes EGDe (LM) was inhibited by CGAS001 (CG). (B) The crude extract showed narrow spectrum antimicrobial activity against selected Gram-positive and negative bacteria using the disk diffusion method. The extract was active against L. monocytogenes EGDe and Enterococcus devriesei K8-ED (ED), but inactive against Staphylococcus aureus (SA) and Escherichia coli (EC).