TABLE 2.
VF class | Virulence factors | Related genes |
Adherence | Fibronectin-binding protein | Fbp |
GroEL | groEL | |
LPS O-antigen (Pseudomonas aeruginosa) | wbpI | |
Regulation | CheA/CheY (Listeria) | cheY |
LisR/LisK (Listeria) | lisR | |
VirR/VirS (Listeria) | virR | |
Toxin | Alpha-clostripain | cloSI |
Hemolysin | Undetermined | |
Undetermined | ||
Copper uptake | Copper exporter (Mycobacterium) | ctpV |
Glycosylation system | O-linked flagellar glycosylation (Campylobacter) | neuB2 |
Immune evasion | Capsule (Staphylococcus) | capF |
capG | ||
4I | ||
Polysaccharide capsule (Bacillus) | galE | |
gtaB | ||
Intracellular survival | Sugar-uptake system (Listeria) | hpt |
Iron uptake | Periplasmic binding protein-dependent ABC transport systems (Vibrio) | vctC |
Lipid and fatty acid metabolism | Pantothenate synthesis (Mycobacterium) | panD |
Magnesium uptake | Mg2+ transport (Salmonella) | mgtB |
Motility | Flagella (Helicobacter) | fliP |
Others | O-antigen (Yersinia) | ddhA |
Phagosome arresting | Nucleoside diphosphate kinase (Mycobacterium) | ndk |
Secretion system | Type III secretion system (Chlamydia) | cdsN |
Serum resistance and immune evasion | LPS (Francisella) | wbtE |
Stress adaptation | Catalase-peroxidase (Mycobacterium) | katG |
*Identified in Virulence Finder Database (VFDB) 2019 web server.