Table 1.
No. | Intervention | Selected population | Phase | ClinicalTrials.gov identifier: |
---|---|---|---|---|
1. | Sipuleucel-T with Radium -223 versus Sipuleucel-T alone | Minimally symptomatic or asymptomatic mCRPC | II | NCT02463799 |
2. | Radiation therapy with Sipuleucel-T versus Sipuleucel-T alone | Hormone resistance metastatic PCa | II | NCT01807065 |
3. | Combination of radiation and Sipuleucel-T | mCRPC | Observational study | NCT02232230 |
4. | Sipuleucel-T and stereotactic ablative body radiation | mCRPC | II | NCT01818986 |
I | NCT01833208 | |||
5. | Sipuleucel-T + oral Indoximod | mCRPC | II | NCT01560923 |
6. | Sipuleucel T with Ipilimumab | Advanced prostate cancer | I | NCT01832870 |
7. | Immediate versus delayed co treatment with Sipuleucel T + Ipilimumab | Chemotherapy naïve mCRPC | II | NCT01804465 |
8. | ProstAtak + valacyclovir with radiation versus placebo + valacyclovir with radiation | Localised PCa | III | NCT01436968 |
9. | PROSTVAC in Combination with Nivolumab | mCRPC | I/II | NCT02933255 |
10. | Enzalutamide with ProstVac-V/F versus Enzalutamide alone | Non metastatic castration sensitive pCa | II | NCT01875250 |
11. | Enzaluatmide with ProstVac-V/F versus Enzalutamide alone | mCRPC | II | NCT01867333 |
12. | ProstVac-V/F + bi-functional fusion protein MSB0011359C + CV301 vaccine | Biochemically recurrent pCa | II | NCT03315871 |
13. | Ad5-PSA | Hormone refractory metastatic pCa | II | NCT00583024 |
14. | Ad5-PSA with ADT (androgen deprivation therapy) versus Ad5-PSA alone | Recurrent pCa after local therapy | II | NCT00583752 |
15. | Pembrolizumab with pTGV-HP Plasmid DNA Vaccine | Hormone resistance metastatic pCa | I/II | NCT02499835 |
16. | pTGV-HP vaccine with GM-CSF versus GM-CSF alone | Non metastatic pCa | II | NCT01341652 |
Ad5, adenovirus type 5; GM-CSF, granulocyte-macrophage colony-stimulating factor; mCRPC, metastatic castration resistant PCa; PCa, prostate cancer; PSA, prostate specific antigen.