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. 2020 Sep 3;12:1756287220951404. doi: 10.1177/1756287220951404

Table 1.

Selected ongoing clinical trials in the treatment of PCa.

No. Intervention Selected population Phase ClinicalTrials.gov identifier:
1. Sipuleucel-T with Radium -223 versus Sipuleucel-T alone Minimally symptomatic or asymptomatic mCRPC II NCT02463799
2. Radiation therapy with Sipuleucel-T versus Sipuleucel-T alone Hormone resistance metastatic PCa II NCT01807065
3. Combination of radiation and Sipuleucel-T mCRPC Observational study NCT02232230
4. Sipuleucel-T and stereotactic ablative body radiation mCRPC II NCT01818986
I NCT01833208
5. Sipuleucel-T + oral Indoximod mCRPC II NCT01560923
6. Sipuleucel T with Ipilimumab Advanced prostate cancer I NCT01832870
7. Immediate versus delayed co treatment with Sipuleucel T + Ipilimumab Chemotherapy naïve mCRPC II NCT01804465
8. ProstAtak + valacyclovir with radiation versus placebo + valacyclovir with radiation Localised PCa III NCT01436968
9. PROSTVAC in Combination with Nivolumab mCRPC I/II NCT02933255
10. Enzalutamide with ProstVac-V/F versus Enzalutamide alone Non metastatic castration sensitive pCa II NCT01875250
11. Enzaluatmide with ProstVac-V/F versus Enzalutamide alone mCRPC II NCT01867333
12. ProstVac-V/F + bi-functional fusion protein MSB0011359C + CV301 vaccine Biochemically recurrent pCa II NCT03315871
13. Ad5-PSA Hormone refractory metastatic pCa II NCT00583024
14. Ad5-PSA with ADT (androgen deprivation therapy) versus Ad5-PSA alone Recurrent pCa after local therapy II NCT00583752
15. Pembrolizumab with pTGV-HP Plasmid DNA Vaccine Hormone resistance metastatic pCa I/II NCT02499835
16. pTGV-HP vaccine with GM-CSF versus GM-CSF alone Non metastatic pCa II NCT01341652

Ad5, adenovirus type 5; GM-CSF, granulocyte-macrophage colony-stimulating factor; mCRPC, metastatic castration resistant PCa; PCa, prostate cancer; PSA, prostate specific antigen.