Table 5.
Comparison of the Risk of Malignancy in BSRTC Categories and by Degree of Hürthle Cell Presence Between (A) Multi-Institutional FNA Cohort (All FNAs with All Patients Going to Surgery)* Results and (B) the Current Study (All FNAs with Hürthle Cell Change with All Patients Going to Surgery)
| Diagnostic category | A. ROM in all FNAs (n = 1827), % | B. ROM in Hürthle cell FNAs (n = 300), % | p† | Degree of Hürthle cell presence (n = 203) |
|||||
|---|---|---|---|---|---|---|---|---|---|
| Mild, n (ROM %) | p | Moderate, n (ROM %) | p | Predominant, n (ROM %) | p | ||||
| I. Nondiagnostic | 25.3 | 7.1 | 0.138 | 3 (0) | 0.32 | 0 (0) | N/A | 6 (16.7) | 0.64 |
| II. Benign | 9.3 | 7.1 | 0.464 | 50 (4) | 0.21 | 6 (0) | 0.434 | 11 (27.3) | 0.048 |
| III. AUS/FLUS | 31.2 | 15.2 | 0.054 | 4 (0) | 0.179 | 3 (33.3) | 0.938 | 19 (21.1) | 0.352 |
| IV. FN/SFN | 33.2 | 20.8 | 0.011 | 2 (0) | 0.32 | 1 (0) | 0.48 | 91 (18.7) | 0.01 |
| V. SM | 82.6 | 50 | 0.006 | 0 (0) | N/A | 3 (33.3) | 0.029 | 3 (66.7) | 0.474 |
| VI. Malignant | 99.1 | 100 | 0.869 | 0 (0) | N/A | 0 (0) | N/A | 1 (100) | 0.924 |
*
Faquin et al. (9).
†
The p-values were calculated with the two-tailed t-test; significance was set at <0.05.
N/A, not applicable.