FIG. 3.

Representative histological sections (H&E, Masson's Trichrome, and Picrosirius Red stains, 20 × magnification) of all treatment groups after 30 days. At 30 days postprocedure, there are general cases of epidermal and dermal hyperplasia and hyperkeratosis (black arrows), and immature collagen deposition (comparison of vibrant stain in native tissue compared with pale pink by H&E, pale blue by Masson's Trichrome, and pale red by Picrosirius Red) predominantly involving the papillary dermis and upper reticular dermis. Dermal appendages such as hair follicles (green arrowheads), smooth muscle (orange arrows, confirmed with alpha smooth muscle actin, not shown), or glands (white arrowheads) appear in multiple cases. Scales: 2 mm. H&E, Hematoxylin and Eosin.