Kaplan–Meier survival curve matrix of disease-specific survival comparing surgery with nonoperative cohorts, with increasing size and age. (A) Age 14–55 years, tumor size 0–4 cm. (B) Age 14–55 years, tumor size 4.1–6 cm. (C) Age 14–55 years, tumor size >6 cm. (D) Age 56–75 years, tumor size 0–4 cm. (E) Age 56–75 years, tumor size 4.1–6 cm. (F) Age 56–75 years, tumor size >6 cm. (G) Age >75 years, tumor size 0–4 cm. (H) Age >75 years, size 4.1–6 cm. (I) Age >75 years, tumor size >6 cm. Color images are available online.