Table 1.

Summary of the PICOS elements for the systematic review

Participants	Participants with VI from an unspecified cause or due to one of the leading causes of VI globally (ie, cataract, uncorrected refractive error, diabetic retinopathy, glaucoma, AMD, corneal opacity and trachoma).
Interventions	Any report that provides information about costs of illness, burden of diseases and/or loss of well-being in participants with VI or eye disease potentially leading to VI.
Comparators	Not relevant
Outcomes	Direct costs, indirect costs, productivity losses, informal care and intangible costs (eg, Quality Adjusted Life Years, Disability Adjusted Life Years), transfer payments and deadweight losses.
Study Design	Partial economic evaluation studies such as cost of illness studies, burden of illness/diseases and full economic evaluation studies, such as cost-effectiveness and cost–benefit studies. Model-based economic evaluation studies not reporting any primary cost data or based on reviews of existing economic studies will be excluded.

AMD, age-related macular degeneration.