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. 2020 Sep 7;37:100756. doi: 10.1016/j.nmni.2020.100756

FIG. 1.

FIG. 1

Anti-viral effect of dornase alfa against SARS-CoV-2. (a) Cytopathic effect (CPE) in MDBK cells infected with SARS-CoV-2 (10 × TCID50) along with dornase alfa in a dose-dependent manner for 8 days. (b) Detected cycle of real-time PCR fluorescence intensity of the SARS-CoV-2 RNA genome that were pre-incubated with dornase alfa at different doses. PC, positive control, synthetic E or Orf1ab genes. NC, negative control, dH2O. (c) The bar graphs showing cycle threshold (Ct) values of the dornase-alfa-treated SARS-CoV-2 samples, PC, and NC in (b). ∗p < 0.05; NS, not significant.