FIG. 2.

Cytopathic effect of SARS-CoV-2–dornase alfa incubated Vero cells in real-time cell analysis (RTCA). (a) Representative normalized cell index histogram showing proliferating viable cells that were control only Vero (green line), 100 U (blue line) or 10 U (purple line) dornase alfa-preincubated SARS-CoV-2 (blue line), and only 10 × TCID₅₀ dose of SARS-CoV-2 (red line). Cell index was normalized based on the values at the end of 24-hour pre-culture. (b) Bar graph showing quantification of the normalized cell index value of the conditions treated with the SARS-CoV-2 along with/without dornase alfa. (c) Bar graph showing normalized cytopathic effect (% CPE) using values of normalized cell index. ∗p < 0.05; NS, not significant.