Table 3.
Confirmation of Changes in the Vitreous Humor Proteome Using PRM Analyses
| Fold Change | Fold Change | |||||
|---|---|---|---|---|---|---|
| Accession | Symbol | Description | Diabetic * | P Value | Diab + Sgp130Fc † | P Value |
| O35945 | Aldh1a7 | Aldehyde dehydrogenase, cytosolic 1 | 6.71 | 0.0116 | 3.24 | 0.8255 |
| P22599 | Serpina1b | Alpha-1-antitrypsin 1-2 | 10.78 | 0.0461 | 1.18 | 0.3521 |
| Q00623 | Apoa1 | Apolipoprotein A-1 | 515.5 | 0.0140 | 33.15 | 0.9006 |
| P01027 | C3 | Complement C3 | 209.3 | 0.0004 | 12.77 | 0.5185 |
| P17183 | Eno2 | Gamma-enolase | 10.51 | 0.0181 | 2.30 | 0.2210 |
| Q9JI02 | Scgb2b20 | Secretoglobin family 2B member 20 | 6.27 | 0.0176 | 0.61 | 0.0688 |
| Q03734 | Serpina3m | Serine protease inhibitor A3M | 12.05 | 0.0382 | 0.99 | 0.4340 |
| P05213 | Tuba1b | Tubulin alpha-1B chain | 59.0 | 0.0360 | 23.13 | 0.0790 |
| P68372 | Tubb4b | Tubulin beta-4B chain | 54.47 | 0.0481 | 27.67 | 0.3364 |
*
Diabetic versus controls.
†
Diabetic with sgp130Fc treatment versus controls.