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. 2020 Aug 11;9:e54051. doi: 10.7554/eLife.54051

Figure 8. Arbitration signals in neuromodulatory ROI.

Activation of the dopaminergic midbrain was associated with arbitrating in favor of individually learned information. Activation (red) is shown at p<0.05 FWE corrected for the full anatomical ROI comprising dopaminergic, cholinergic, and noradrenergic nuclei (yellow).

Figure 8.

Figure 8—figure supplement 1. Neuromodulatory nuclei anatomical mask.

Figure 8—figure supplement 1.

The mask for ROI analyses included (i) the dopaminergic midbrain (substantia nigra, SN, and ventral tegmental area, VTA), (ii) the cholinergic basal forebrain, (iii) cholinergic nuclei in the tegmentum of the brainstem, that is, the pedunculopontine tegmental (PPT) and laterodorsal tegmental (LDT) nuclei, and (iv) the noradrenergic locus coeruleus (LC).