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. 2020 Jul 6;44(5):645–654. doi: 10.1093/femsre/fuaa027

Figure 2.

Figure 2.

Schematic drawing of a mucin monomer. Each mucin monomer consists of a protein core called the PTS domain that is comprised primarily of proline, threonine and serine. O-glycosylation of polysaccharides occurs at PTS domains between cysteine rich domains. Typically, the C-terminus of the protein backbone contains a cysteine knot and the N-terminus contains several von Willebrand D (VWD) domains.