Figure 1.

TRIM24 is upregulated and negatively correlated with survival prognosis in colorectal cancer. (A), Copy number analysis of TRIM24 in the TCGA colon cancer dataset. The data were downloaded from http://xena.ucsc.edu/public‐hubs. (B), TRIM24 mRNA expression in tumor and normal specimens. TRIM24 mRNA expression was obtained from the TCGA dataset from http://xena.ucsc.edu/public‐hubs. (C), A total of 80 clinical colorectal cancer and paired peri‐tumoral tissues were analyzed by immunohistochemistry (IHC). Representative images of TRIM24 expression in serial sections from colorectal cancer tissues are shown. Scale bars: 50 μm. (D), Kaplan‐Meier analyses of TRIM24 high or low expression patients categorized based on IHC. Error bars show ± SD. ***P < 0.001. The data represent the results from three independent experiments