TABLE 1.
Overview of SOX17 and SOX2 expression patterns in (pre)malignant lesions of the uterine cervix. The different classes of SOX17 and SOX2 combinations are based on staining intensity and percentage of positive cells
| Type of tissue | SOX17+ only | SOX2+ only | SOX17+/SOX2+ | SOX17−/SOX2− | ||
|---|---|---|---|---|---|---|
| LSIL | n = 17 | 1 | 12 | 3 | 1 | |
| HSIL | n = 33 | 0 | 26 | 4 | 3 | |
| Co‐existent SIL/AIS | n = 10 | SIL | 1 | 7 | 1 | 1 |
| AIS | 5 | 1 | 3 | 1 | ||
| SCC | n = 20 | 0 | 20 | 0 | 0 | |
Abbreviations: AIS, adenocarcinoma in situ; HSIL, high‐grade SIL; LSIL, low‐grade squamous intraepithelial lesion; SCC, squamous cell carcinoma.