TABLE 3.
SOX expression patterns in areas of morphologically normal squamous epithelium (40 areas in 18 SIL cases) either distant from (27 areas) or adjacent/in close proximity (13 areas) to the lesions
| Type of tissue | SOX17+ only | SOX2+ only |
SOX17+ SOX2+ |
SOX17− SOX2− |
||
|---|---|---|---|---|---|---|
| Morphologically normal areas of squamous epithelium including remnants of (immature) metaplasia | n = 27 | 9 | 17 | 0 | 1 | |
| Morphologically normal squamous epithelium adjacent to squamous intraepithelial lesion (SIL) including (remnants) of immature metaplasia |
LSIL n = 8 |
1 | 7 | 0 | 0 | |
|
HSIL n = 5 a |
2 | 3 | 0 | 0 | ||
| SIL |
LSIL n = 8 |
0 | 7 | 0 | 1 | |
| 0 | 10 | 0 | 0 | |||
|
HSIL n = 10 | ||||||
Abbreviations: HSIL, high‐grade intraepithelial lesion; LSIL, low‐grade squamous intraepithelial lesions.
a
From the 10 samples of HSIL shown in Table 2, only 5 showed morphologically normal squamous epithelium adjacent to the HSIL.