Table 1.
Clinical and laboratory dataa.
| Case | Age | Obesity | Co-morbidity | ANC (x103) | LDH (U/L) | Platelets (x109/L) | INR | CRP (mg/dL)/IL-6 (pg/ml) | Fibrinogen (mg/dL) Pre- Post- argatroban | Ferritin (ng/mL) | CK (U/L) | AST/ALT (U/L) | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 77 | Overwt. | HTN | 13.3 | 1037 | 183 | 1.2 | >30.4/ND | 815 | 392 | 2793 | 2130 | 461/258 |
| 2 | 55 | Overwt. | Renal transplant, a. fib. | 14.8 | 456 | 114 | 1.2 | 24.4/125 | 585 | 146 | 8699 | 64 | 102/36 |
| 3 | 56 | No | DM, CKD | 25.9 | 2254 | 107 | 1.2 | 22.6/25 | 586 | 242 | 4713 | >7800 | 1027/538 |
| 4 | 65 | Overwt. | HTN, HLD | 22.1 | 772 | 232 | 1.0 | 15.2/<5 | 855 | 397 | 2020 | 87 | 540/181 |
| 5 | 65 | No | HTN, HLD, DM2 | 14.9 | 847 | 152 | 1.2 | 26.2/18 | 672 | ND | 2564 | 1551 | 151/112 |
a
Laboratory values represent peak values for the period preceding recognition of CCRT circuit thrombosis. Obesity: overweight, body mass index (BMI) > 25 but <30. HTN, hypertension. HLD, hyperlipidemia. DM2, type 2 diabetes. A. fib., atrial fibrillation. CKD, chronic kidney disease. ANC, absolute neutrophil count. LDH, lactate dehydrogenase (nl. 118–230 U/L). Plts, platelet count. INR, International Normalized Ratio. CRP, C-reactive protein (nl ≤ 0.9mg/dL). IL-6, interleukin-6 (nl ≤ 5pg/ml). CR, creatine kinase (nl. 34–145 U/L). AST, aspartate transaminase (nl. ≤34U/L). ALT, alanine transferase (nl. 10–49U/L). Ferritin, nl.10–291ng/ml. Fibrinogen, nl.180–400 mg/dL.