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Agents which may prevent the development of actinic keratoses and squamous cell carcinoma in high-risk patients
| Therapy | Agent | Dosage |
|---|---|---|
| Topical therapy | Sunscreens (especially those containing DNA-photolyase) | Apply twice daily in photo-exposed areas |
| 5% 5-FU | Apply twice daily for 30 days. Two or three courses per year may be indicated | |
| Oral therapy | Retinoids |
Retinol 25,000 IU/day Acitretin 25 mg/daily |
| Nicotinamide | 500 mg twice daily |
