Table 3. Identified polymorphisms in MC1R gene from seven duck populations.
| Nucleotide position | Amino acid change | Effect on protein due to amino acid change | Effect on protein function due to substitution* |
|---|---|---|---|
| c.52A>G | Missense, p.Lys18Glu | Basic to acidic | 0.753, Neutral |
| c.376A>G | Missense, p.Ile126Val | Non-polar to Non-polar | −0.074, Neutral |
| c.409G>A | Missense, p. Ala 137Thr | Non-polar to Polar (uncharged) | −3.935, Deleterious |
| c.649C>T | Missense, p.Arg217Cys | Polar (positively charged) to Polar (uncharged) | −5.893, Deleterious |
| c.650G>A | Missense, p.Arg217His | Polar (positively charged) to Polar (positively charged) | −3.047, Deleterious |
| g.1019C>T | Not applicable | ||
| g.1020A>G | Not applicable | ||
| g.1023C>T | Not applicable | ||
| g.1024A>G | Not applicable | ||
| g.1028A>G | Not applicable | ||
| g.1033A>G | Not applicable | ||
| g.1038A>G | Not applicable |
*
Variants with a score above −2.5 are considered “neutral” and variants with a score equal to or below −2.5 are considered “deleterious” (Choi et al., 2012)