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. 2020 Sep 7;10:14688. doi: 10.1038/s41598-020-71718-z

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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TES effect on mice body weight. (A) Representation of total body weight before and after 21 days of surgery (n = 20). Data are presented as mean ± SEM. A paired samples T-test was used to compare each time point. **p = 0.005. (B) Representation of total body weight before castration (n = 20) and after 14 days of continuous administration in both TES-receiving groups (n = 12). Data are presented as mean ± SEM. An independent samples T-test was used to compare each data. n.s.—non-significant.