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Knockdown of Pex3 in the Drosophila eye phenocopies the Rosy phenotype. (A) Wild type Drosophila eye pigment is a bright red-orange color. (B) Reduction of Pex3 activity specifically in the eye by a combination of eyeless(ey) GAL4 and a UAS inducible transgene expressing a dsRNA targeting Pex3 mRNA causes the characteristic dark red pigmentation associated with ry mutations. Bar = 300 μm.
