TABLE 1.
Drosophila homologs of human Pex proteins.
| Human | Role | Drosophila | Loc | Func | Protein interactions |
| PEX1 | Protein import | Pex1 | (+)B | M | |
| PEX2 | Protein import | Pex2 | (+)B | M | |
| PEX3 | Membrane assembly | Pex3 | (−)B | M | Pex19 (FlyBi) |
| PEX5 | Protein import | Pex5 | (+)B | M | Pex14 (G) |
| PEX6 | Protein import | Pex6 | (+)B | M | |
| PEX7 | Protein import | Pex7 | (+)B | ||
| PEX10 | Protein import | Pex10 | (+)B | ||
| PEX11A/B | Fission | Pex11 | (+)B | M | |
| PEX11C | Fission | CG13827 | (+)B | ||
| PEX11C | Fission | CG33474 | (+)B | ||
| PEX12 | Protein import | Pex12 | (+)B | M | |
| PEX13 | Protein import | Pex13 | (+)B | M | |
| PEX14 | Protein import | Pex14 | (+)B | M | Pex5 (G) |
| PEX16 | Membrane assembly | Pex16 | (+)B | M | |
| PEX19 | Membrane assembly | Pex19 | (+)B | M | Pex3 (FlyBi) |
“Loc”: (+) validated localization of the protein to the peroxisome, (−) did not localize to peroxisomes in B-(Baron et al., 2016). “Func”: experimental confirmation of an effect on peroxisome proliferation in fly cells M-(Mast et al., 2011). Protein interactions indicate interaction between these protein partners in large-scale yeast 2-hybrid (FlyBi) or (G) whole proteome mass-spectrometric identification (Guruharsha et al., 2011).