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. 2020 Aug 25;8:835. doi: 10.3389/fcell.2020.00835

TABLE 2.

Drosophila homologs of known peroxisomal membrane proteins.

Human Role Drosophila Loc
ABCD1/2 Fatty acid transporter ABCD ATP binding cassette subfamily D (+)B
ABCD3 Fatty acid transporter Pmp70 Peroxisomal membrane protein 70 kDa (+)B
ATP2C1 Ca2+ transporter SPoCk Secretory pathway calcium atpase (−)B
BEST4 Channel Best2 Bestrophin 2 (+)C
FAR1/2 Ether lipid synthesis CG5065 Fatty acyl-CoA reductase (+)B
FIS1 Peroxisome fission Fis1 Fission, mitochondrial 1 (−)B
MP17L ROS metabolism CG12355 (−)B
MVP17/PMP22/PXMP2 Channel CG11077 (+)B
SLC27A1/4 Fatty acid transporter Fatp1 Fatty acid transport protein 1 (−)B
SLC22A5 Carnitine transporter Orct Organic cation transporter (+)B
SLC25A17 Transporter PMP34 Peroxisomal membrane protein 34 (+)B,F
TMEM135 CG11737 (+)B
MFF Fission Tango11 Transport and Golgi organization 11

“Loc”: (+) experimentally validated localization to peroxisomes, (−) did not localize to peroxisomes in B-(Baron et al., 2016), F-(Faust et al., 2012) or (C-Chintapalli et al., 2012).