TABLE 2.
Human | Role | Drosophila | Loc | |
ABCD1/2 | Fatty acid transporter | ABCD | ATP binding cassette subfamily D | (+)B |
ABCD3 | Fatty acid transporter | Pmp70 | Peroxisomal membrane protein 70 kDa | (+)B |
ATP2C1 | Ca2+ transporter | SPoCk | Secretory pathway calcium atpase | (−)B |
BEST4 | Channel | Best2 | Bestrophin 2 | (+)C |
FAR1/2 | Ether lipid synthesis | CG5065 | Fatty acyl-CoA reductase | (+)B |
FIS1 | Peroxisome fission | Fis1 | Fission, mitochondrial 1 | (−)B |
MP17L | ROS metabolism | CG12355 | (−)B | |
MVP17/PMP22/PXMP2 | Channel | CG11077 | (+)B | |
SLC27A1/4 | Fatty acid transporter | Fatp1 | Fatty acid transport protein 1 | (−)B |
SLC22A5 | Carnitine transporter | Orct | Organic cation transporter | (+)B |
SLC25A17 | Transporter | PMP34 | Peroxisomal membrane protein 34 | (+)B,F |
TMEM135 | CG11737 | (+)B | ||
MFF | Fission | Tango11 | Transport and Golgi organization 11 |
“Loc”: (+) experimentally validated localization to peroxisomes, (−) did not localize to peroxisomes in B-(Baron et al., 2016), F-(Faust et al., 2012) or (C-Chintapalli et al., 2012).