Table 4.
Previous studies which described reported incidence of cardiac injury and its association with mortality in COVID-19.
| Study 1 (9) | Study 2 (6) | Study 3 (5) | Study 4 (4) | Study 5 (3) | Study 6 (24) | |
|---|---|---|---|---|---|---|
| First author | Shaobo Shi | Tao Guo | Dawei Wang | Fei Zhou | Tao Chen | Shaobo Shi |
| Publication date | 3/25 | 3/27 | 2/7 | 3/9 | 3/26 | 5/6 |
| Data source | Renmin Hospital of Wuhan University | Seventh Hospital of Wuhan City | Zhongnan Hospital of Wuhan University | Jinyintan Hospital and Wuhan Pulmonary Hospital | Tongji Hospital | Renmin Hospital of Wuhan University |
| Date of data collection | 1/20–2/10 | 1/23–2/23 | 1/1–2/28 | 12/29–1/31 | 1/13–2/12 | 1/1–2/23 |
| Sample size | 416 | 187 | 138 | 191 | 274 | 671 |
| Grouping | Cardiac injury (n = 82)/ramyano cardiac injury (n = 334) | Elevated TnT (n = 52)/normal TnT (n = 135) | ICU (n = 36)ramya/non-ICU (n = 102) | Death (n = 54)ramya/survivor (n = 137) | Deaths (n = 113)ramya/recovered (n = 161) | Death (n = 62)ramya/survivor (n = 609) |
| Study type | Cohort | Cohort | Descriptive | Case–control | Descriptive | Case–control |
| Overall age | 64 (21–95) | 58.50 (14.66) | 56 (42–68) | 56.0 (46.0–67.0) | 62.0 (44.0–70.0) | 63 (50–72) |
| Grouping age(year) | 74 (34–95)/ramya60 (21–90) | 71.40 (9.43)/ramya53.53 (13.22) | 66 (57–78)/ramya51 (37–62) | 69.0 (63.0–76.0)/ramya52.0 (45.0–58.0) | 68.0 (62.0–77.0)/ramya51.0 (37.0–66.0) | 74 (66–81)/ramya61 (49–70) |
| Overall hypertension (percentage) | 30.5 | 32.6 | 31.2 | 30 | 34 | 29.7 |
| Grouping hypertension (percentage) | 59.8/23.4 | 63.5/20.7 | 58.3/21.6 | 48/23 | 48/24 | 59.7/26.6 |
| Overall DM (percentage) | 14.4 | 15.0 | 10.1 | 19 | 17 | 14.5 |
| Grouping DM (percentage) | 24.4/12.0 | 30.8/8.9 | 22.2/5.9 | 31/14 | 21/14 | 27.7/13.1 |
| Overall CHD (percentage) | 10.6 | 11.2 | — | 8 | — | 8.9 |
| CHD (percentage) | 29.3/6.0 | 32.7/3.0 | — | 24/1 | — | 33.9/6.4 |
| Overall COPD (percentage) | 2.9 | 2.1 | 2.9 | 3 | — | 3.4 |
| COPD (percentage) | 7.3/1.8 | 7.7/0 | 8.3/1.0 | 7/1 | — | 3.2/3.4 |
| hs-TNI (pg/mL) | 190 (80–1,120)/ <6 (<6–9) | — | 11.0 (5.6–26.4)/5.1 (2.1–9.8) | 22.2 (5.6–83.1)/3.0 (1.1–5.5) | 40.8 (14.7–157.8)/3.3 (1.9–7.0) | 0.235 (0.042–1.996)/0.006 (0.006–0.011) |
| Cardiac injury (percentage) | 19.7 | 27.8 | — | — | — | 75.8/9.7 |
| Overall mortality (percentage) | 13.7 | 23 | 4.3 | 28.3 | 14.1 | 9.2 |
| Grouping mortality (percentage) | 51.2/4.5 | 59.6/8.9 | — | — | — | — |
COVID-19, coronavirus disease 2019; DM, diabetes mellitus; CHD, chronic heart disease; COPD, chronic obstructive pulmonary disease; hs-Tni, high-sensitivity troponin I.