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. 2020 Aug 25;10:1451. doi: 10.3389/fonc.2020.01451

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Copyright © 2020 Zhu, Liu, Lu, Zhang, Zhang, Chen and Deng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Transcriptome analysis of ovarian cancer cells with EGFL6 knockout. (A) Venn diagram shows the number of co-expressed genes and unique genes expressed by SKOV3 and E10, respectively. (B) Scatter plot of co-expressed genes between SKOV3 and E10. (C) KEGG enrichment of scatter plot. (D) Cluster analysis of differential gene expression pattern. (E) Western blot assays of signal pathways related to proliferation, apoptosis, migration, invasion, and angiogenesis in the cancer cells with EGFL6 knockout. *p < 0.05 were considered statistically significant.