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. 2020 Aug 25;11:994. doi: 10.3389/fgene.2020.00994

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Copyright © 2020 Li, Wang, Huang, Zhang, Wang and Wan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Differential clinicopathological features, clinical outcomes and malignancy of lung adenocarcinoma between cluster 1 and cluster 2. (A) Cluster 2 was found significantly correlated with male patients, higher T stage and higher M stage compared to cluster 1. (B) Significantly shorter overall survival (OS) was observed in cluster 2 than in cluster 1. (C) Gene ontology (GO) enrichment analysis of genes that were significantly dysregulated in cluster 2. (D) Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis of genes that were significantly dysregulated in cluster 2. *P < 0.05, **P < 0.01, ***P < 0.001.