Table 1.
HC | BIP | SCZ | HC v. BIP | HC v. SCZ | BIP v. SCZ | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
N = 622 | N = 263 | N = 607 | χ2/t | p | χ2/t | p | χ2/t | p | ||||
Sex (% female) | 0.46 | 0.63 | 0.39 | 19.98 | 0.000 | 6.92 | 0.009 | 42.04 | 0.000 | |||
Mean | s.d. | Mean | s.d. | Mean | s.d. | |||||||
Age (years) | 30.06 | 6.91 | 27.56 | 6.34 | 27.04 | 6.50 | −5.12 | 0.000 | −7.96 | 0.000 | −1.10 | 0.278 |
Education (years) | 14.32 | 2.25 | 13.27 | 2.26 | 12.17 | 2.35 | −6.00 | 0.000 | −15.85 | 0.000 | −6.10 | 0.000 |
Birth weight (grams)a | 3521 | 538 | 3556 | 558 | 3481 | 576 | 1.40 | 0.162 | −1.57 | 0.117 | −2.38 | 0.018 |
Gestation age (weeks) | 39.91 | 1.78 | 39.88 | 1.93 | 39.61 | 2.49 | −0.14 | 0.887 | −2.42 | 0.016 | −1.57 | 0.117 |
Age at illness onset | 19.03 | 5.99 | 21.89 | 6.17 | 6.28 | 0.000 | ||||||
Illness duration (years) | 8.58 | 6.45 | 5.21 | 5.35 | −7.92 | 0.000 | ||||||
PANSS | 45.98 | 10.06 | 62.45 | 16.62 | 14.71 | 0.000 | ||||||
General | 25.66 | 5.80 | 32.04 | 8.40 | 11.07 | 0.000 | ||||||
Negative | 10.33 | 3.64 | 15.41 | 6.24 | 12.15 | 0.000 | ||||||
Positive | 10.06 | 3.65 | 14.94 | 5.16 | 13.73 | 0.000 | ||||||
GAF-S | 56.86 | 11.37 | 42.92 | 11.89 | −15.96 | 0.000 | ||||||
GAF-F | 55.19 | 12.95 | 44.58 | 12.21 | −11.47 | 0.000 | ||||||
Premorbid IQb | 112.99 | 1.72 | 112.22 | 1.71 | 110.04 | 1.75 | 0.48 | 0.631 | −4.79 | 0.000 | −3.61 | 0.000 |
Current full scale IQc | 113.30 | 5.16 | 108.74 | 4.89 | 100.79 | 5.26 | −2.19 | 0.028 | −10.33 | 0.000 | −5.32 | 0.000 |
IQ difference scored | 0.34 | 3.64 | −3.45 | 3.39 | −8.45 | 3.72 | −2.81 | 0.005 | −9.19 | 0.000 | −4.20 | 0.000 |
Adjusted for sex; s.d. (standard deviation); HC (healthy controls); BIP (bipolar spectrum); SCZ (schizophrenia spectrum); PANSS (Positive and Negative Syndrome Scale); GAF-S (Global Assessment of Functioning- symptoms); GAF-F (Global Assessment of Functioning-functioning). Bold numbers represent significant values.
NART premorbid IQ estimate adjusted for age, education and sex (HC: N = 582, BIP: N = 230 and SCZ: N = 411).
WASI full scale IQ assessment adjusted for age, education and sex (HC: N = 580, BIP: N = 235 and SCZ: N = 428).
IQ difference score (current IQ – premorbid IQ) adjusted for age, education and sex (HC: N = 579, BIP: N = 228 and SCZ: N = 396)