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. 2020 Aug 25;11:931. doi: 10.3389/fneur.2020.00931

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Copyright © 2020 Zhang, Peng, Zhang, Li, Liu, Zhao, Yin, Liang and Wei.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Flow-chart illustrating the selection process for this study of the association among MMP-9, vertebrobasilar ectasia (VBE), and vertebral artery dominance (VAD) in patients with vertigo or dizziness who also have vascular risk factors. MRA was used to identify patients with VBE and VAD among a group of 285 consecutive patients. Blood samples were drawn from patients that met the inclusion and exclusion criteria. The patients were divided into VBE-negative and VBE-positive groups, each of which was subdivided into non-VAD and VAD subgroups. Finally, the associations of MMPs, VBE, and VAD were analyzed.