Table 2.
Prognostic analysis of DUXAP8 and target genes for overall survival
| Long non-coding RNA | Patients | Overall survival | |||||
|---|---|---|---|---|---|---|---|
| (n=370) | No. of event | MST (days) | HR (95%CI) | Crude P value | HR (95%CI) | Adjusted P value§ | |
| DUXAP8 | |||||||
| Low expression | 185 | 56 | 2131 | Ref. | 0.001 | Ref. | 0.014 |
| High expression | 185 | 74 | 1372 | 1.768 (1.247-2.507) | 1.632 (1.104-2.412) | ||
| RNF2 | |||||||
| Low expression | 185 | 57 | 2131 | Ref. | 0.003 | Ref. | 0.008 |
| High expression | 185 | 73 | 1372 | 1.704 (1.199-2.420) | 1.700 (1.146-2.519) | ||
| MAGEA1 | |||||||
| Low expression | 185 | 59 | 2456 | Ref. | 0.194 | Ref. | 0.480 |
| High expression | 185 | 71 | 1397 | 1.258 (0.889-1.780) | 1.147 (0.784-1.678) | ||
| GABRA3 | |||||||
| Low expression | 185 | 55 | 2486 | Ref. | 0.006 | Ref. | 0.103 |
| High expression | 185 | 75 | 1372 | 1.631 (1.149-2.313) | 1.378 (0.937-2.026) | ||
| MKRN3 | |||||||
| Low expression | 185 | 58 | 2116 | Ref. | 0.180 | Ref. | 0.672 |
| High expression | 185 | 72 | 1560 | 1.267 (0.896-1.792) | 1.086 (0.740-1.595) | ||
| FAM133A | |||||||
| Low expression | 185 | 61 | 1852 | Ref. | 0.110 | Ref. | 0.472 |
| High expression | 185 | 69 | 1397 | 1.325 (0.938-1.872) | 1.152 (0.784-1.694) | ||
| MAGEA3 | |||||||
| Low expression | 185 | 57 | 2486 | Ref. | 0.068 | Ref. | 0.207 |
| High expression | 185 | 73 | 1490 | 1.381 (0.976-1.955) | 1.280 (0.872-1.878) | ||
| CNTNAP4 | |||||||
| Low expression | 185 | 65 | 1694 | Ref. | 0.608 | Ref. | 0.952 |
| High expression | 185 | 65 | 1624 | 1.094 (0.776-1.544) | 0.988 (0.675-1.446) | ||
| MAGEA6 | |||||||
| Low expression | 185 | 56 | 1791 | Ref. | 0.056 | Ref. | 0.186 |
| High expression | 185 | 74 | 1560 | 1.404 (0.992-1.988) | 1.298 (0.882-1.909) | ||
| MALRD1 | |||||||
| Low expression | 185 | 61 | 1852 | Ref. | 0.315 | Ref. | 0.707 |
| High expression | 185 | 69 | 1423 | 1.194 (0.845-1.686) | 1.076 (0.734-1.577) | ||
| DGKI | |||||||
| Low expression | 185 | 61 | 2116 | Ref. | 0.973 | Ref. | 0.170 |
| High expression | 185 | 69 | 1624 | 1.006 (0.712-1.421) | 0.763 (0.518-1.123) | ||
Note: §: P values were adjusted for radical resection, tumor stage and HBV infection; Bold indicates significant P values, NA: not available; MST: median survival time; HR: hazard ratio; 95%CI: 95% confidence interval.