Table 3.
Multivariate Cox regression analysis of OS in AHYMUM and AHNTU cohorts (OS: overall survival) was shown
| Covariates | AHYMUM | AHNTU | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P value | HR | 95% CI | P value | |
| Tumor size (ref. <5cm) | 1.199 | 0.463-3.104 | 0.708 | 0.905 | 0.358-2.283 | 0.832 |
| AJCC stage (ref. II - IV) | 0.763 | 0.256-2.277 | 0.628 | 2.826 | 1.150-6.947 | 0.024 |
| Primary lesion (ref. Single) | 1.151 | 0.514-0.576 | 0.733 | 2.151 | 0.898-5.154 | 0.086 |
| Differential degree (ref. Low) | 2.019 | 0.792-5.147 | 0.141 | 0.925 | 0.377-2.269 | 0.865 |
| Microvascular invasion (ref. Absent) | 1.488 | 0.719-3.081 | 0.284 | 2.023 | 0.783-5.228 | 0.146 |
| Capsular invasion (ref. Absent) | 0.984 | 0.326-2.973 | 0.978 | 1.363 | 0.518-3.585 | 0.530 |
| Okuda score (ref. I) | 2.329 | 1.079-5.027 | 0.031 | 2.819 | 1.105-7.194 | 0.030 |
| RAD50 expression (ref. low) | 6.807 | 2.598-17.839 | <0.001 | 1.735 | 0.753-3.996 | 0.195 |