Table 5.

Diagnostic performance of HSP90 in patients with GC and CRC

Biomarkers		Training group				Validation group
		Sensitivity	Specificity	AUC	Youden index value	Sensitivity	Specificity	AUC	Youden index value
GC	HSP90	84.6%	96.0%	0.956	0.806	84.3%	80.0%	0.888	0.643
	CEA	73.1%	100.0%	0.903	0.731	62.7%	100.0%	0.847	0.627
	CA19-9	40.4%	100.0%	0.636	0.404	47.1%	96.0%	0.762	0.431
CRC	HSP90	88.1%	78.3%	0.888	0.664	95.0%	91.3%	0.962	0.863
	CEA	69.0%	95.7%	0.869	0.647	50.0%	100.0%	0.828	0.500
	CA19-9	64.3%	82.6%	0.777	0.469	52.5%	95.7%	0.699	0.482