Table 2.
Methylation sites of TRIM67 in CRC tissues
| No. | Site | Methylation | Pearson's correlation | ProbeSeq | ||
|---|---|---|---|---|---|---|
| FC | P | R | P | |||
| 1 | -1709 | 0.83 | 0.005 | 0.291 | 0.213 | AATAAACTAAACCTAACAAAATTAAAATCTTATAAAAAAAACCCCTAACC |
| 2 | -722 | 1.37 | 0.045 | -0.434 | 0.056 | AATCCCCRAAATAAATAACACTTAAACTAACAAACAAAACAATAAAAAAC |
| 3 | -678 | 1.20 | 0.011 | -0.500 | 0.025 | AAAACATCACACTACTCACAAAACATAACTACTAACTCTAACAAAATACA (U) AAAACGTCGCACTACTCGCAAAACGTAACTACTAACTCTAACGAAATACG (M) |
| 4 | -359 | 1.31 | 0.028 | -0.484 | 0.031 | TTAAAAAACTTAAAACTCRAAATATAAAACCCRTAACCRCTATCTATCTC |
| 5 | -84 | 1.64 | 0.009 | -0.543 | 0.013 | AACRCAAAACAAACAAACATTATAAAAACAAAACAAAATAATAAACTCCC |
| 6 | 23 | 1.46 | 0.013 | -0.433 | 0.056 | CAACACTACTCTACACTAAAAATAAATAACCAAAACTCAAAAAACTAACA (U) CAACGCTACTCTACGCTAAAAATAAATAACCGAAACTCGAAAAACTAACG (M) |
| 7 | 64 | 1.90 | 0.006 | -0.389 | 0.090 | AAAAAACRTACCCCTCRACTATAAAATAAACATACCCRTATAATACCCCC |
| 8 | 497 | 1.03 | 0.613 | -0.097 | 0.684 | ACAAACAAATACAAAAACCACTCAACCATAAAACTAAAATCAACACCACA (U) ACAAACAAATACGAAAACCGCTCAACCGTAAAACTAAAATCAACACCACG (M) |
| 9 | 670 | 1.25 | 0.438 | -0.161 | 0.497 | AAACCAAAAAAACAAATCAATCCCAACCACAAAAAAAAAACCCCAAAACA (U) AAACCAAAAAAACGAATCAATCCCGACCGCAAAAAAAAAACCCCAAAACG (M) |
| 10 | 706 | 1.26 | 0.262 | 0.022 | 0.928 | RACCCAAAATCAAAAACRCCRCAAAAACAACAACTAAAAACCAAAAAAAC |
| 11 | 925 | 1.94 | 0.008 | -0.284 | 0.225 | CCTTAAAATTACCCCTTAATTCCCTAACAACAAAAAACRAACCCTTATTC |
| 12 | 937 | 1.25 | 0.311 | -0.250 | 0.287 | TCCCTACAAAACCCTTAAAATTACCCCTTAATTCCCTAACAACAAAAAAC |
| 13 | 1057 | 1.67 | 0.032 | -0.103 | 0.664 | CCATTATTTAAATAAAAATTATATCTTAAATCAATACAACRACCTACCCC |
| 14 | 1119 | 1.50 | 0.041 | -0.638 | 0.002 | ATTTCTAAACAACTAACTTTTTAAAATCCCATTTTCACCCTTCTATAACA (U) ATTTCTAAACGACTAACTTTTTAAAATCCCGTTTTCACCCTTCTATAACG (M) |
| 15 | 1158 | 2.06 | 0.028 | -0.522 | 0.018 | RTAATTTTAAAAAACRACTATCAAACCATATTACCTATCCATTTCTAAAC |
Site, distance to transcription start site; FC, fold change of beta value (cancer vs. paired normal tissue); Pearson's correlation, Pearson's correlation between DNA methylation level and TRIM67 expression.