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. 2020 Aug 19;11(20):6070–6080. doi: 10.7150/jca.44367

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ZIC2 was preferentially expressed in LAC and indicated poorer prognosis. (A) mRNA expression of ZIC2 in 20 paired LAC and adjacent normal lung tissues was detected by RT-PCR assays. (B) Protein expression of ZIC2 in 20 paired LAC and adjacent normal lung tissues was detected by WB assays. (C) mRNA expression pattern of ZIC2 between LAC and normal lung tissues were evaluated according to TCGA database. (D) Patients with high ZIC2 expression had significantly shorter overall survival according to TCGA database.