Table 2.

Univariate and multivariate Cox regression analyses of risk factors associated with overall survival in HCC patients

Variables	Univariate analysis			Multivariate analysis
	HR	95%CI	p value	HR	95%CI	p value
SSR2 expression	3.20	1.21-8.49	0.02	3.18	1.05-9.68	0.04
(High vs. Low)
Gender	1.25	0.40-3.92	0.70
(Male vs. Female)
Age (years)	0.50	0.23-1.12	0.09
(≥50 vs.<50)
AFP (ng/mL)	3.61	1.54-8.42	<0.01	3.37	1.33-8.52	0.01
(≥200 vs. <200)
Size (cm)	2.53	1.13-5.67	0.02	1.68	0.65-4.37	0.29
(≥5 vs. <5 )
Tumor nodule number	0.95	0.31-2.87	0.93
(≥2 vs.<2)
Cirrhosis	1.28	0.58-2.81	0.55
(Positive vs. Negative)
MVI	2.29	1.02-5.10	0.04	1.82	0.74-4.45	0.19
(Positive vs. Negative)
Stage	4.34	1.79-10.52	<0.01	2.73	0.98-7.41	0.05
(Late vs. Early)
Encapsulation invasion	2.25	1.01-5.04	<0.05	1.29	0.49-3.41	0.61
(Positive vs. Negative)
Grade	1.89	0.66-5.35	0.23
(Poor vs. Well)