Table 3.

Univariate and multivariate Cox regression analyses of risk factors associated with disease-free survival in HCC patients

Variables	Univariate analysis			Multivariate analysis
	HR	95%CI	p value	HR	95%CI	p value
SSR2 expression	3.59	1.65-7.83	0.02	3.32	1.44-7.65	0.01
(High vs. Low)
Gender	0.88	0.31-2.51	0.81
(Male vs. Female)
Age (years)	0.65	0.32-1.31	0.23
(≥50 vs.<50)
AFP (ng/mL)	1.01	0.46-2.22	0.99
(≥200 vs. <200)
Size (cm)	1.68	0.80-3.51	0.17
(≥5 vs. <5 )
Tumor nodule number	0.77	0.29-2.06	0.61
(≥2 vs.<2)
Cirrhosis	1.66	0.82-3.39	0.16
(Positive vs. Negative)
MVI	2.53	1.22-5.24	0.01	2.20	1.00-4.84	0.05
(Positive vs. Negative)
Stage	3.71	1.45-9.51	0.01	3.05	1.10-8.51	0.03
(Late vs. Early)
Encapsulation invasion	2.44	1.14-5.23	0.02	1.49	0.64-3.47	0.36
(Positive vs. Negative)
Grade	1.14	0.42-3.11	0.80
(Poor vs. Well)