Table 2.
Evaluation of the influence of no cirrhosis/cirrhosis on tumour pathological grade
| Variables | n = 3419 | Univariate analysis | Logistic multivariate regression | |||
|---|---|---|---|---|---|---|
| Well/Moderate No. (%) | Poor/Anaplastic No. (%) | P | OR (95%CI) | P | ||
| Sex | Male | 2128 (78.0) | 520 (75.1) | 0.104 | - | |
| Female | 599 (22.0) | 172 (24.9) | - | |||
| Age | <60 | 1073 (39.3) | 263 (38.0) | 0.518 | - | |
| ≥60 | 1654 (60.7) | 429 (62.0) | - | |||
| Race | White | 1842 (67.5) | 407 (58.8) | < 0.001 | Reference | |
| Black‡ | 362 (13.3) | 92 (13.3) | 1.052 (0.814-1.360) | 0.697 | ||
| Other* | 503 (18.4) | 191 (27.6) | 1.590 (1.297-1.950) | < 0.001 | ||
| Unknown | 20 (0.7) | 2 (0.3) | 0.451 (0.103-1.966) | 0.289 | ||
| Marital Status | Married | 1517 (55.6) | 377 (54.5) | 0.849 | - | |
| Non-married# | 1118 (41.0) | 292 (42.2) | - | |||
| Unknown | 92 (3.4) | 23 (3.3) | - | |||
| Year of diagnosis | 2010-2011 | 779 (28.6) | 189 (27.3) | 0.174 | - | |
| 2012-2013 | 780 (28.6) | 180 (26.0) | - | |||
| 2014-2016 | 1168 (42.8) | 323 (46.7) | - | |||
| AFP | Negative | 879 (32.2) | 107 (15.5) | < 0.001 | Reference | |
| Positive | 1488 (54.6) | 496 (71.7) | 2.834 (2.257-3.559) | < 0.001 | ||
| Borderline | 3 (0.1) | 0 (0.0) | 0.000 (0.000-0.000) | 0.999 | ||
| Unknown | 357 (13.1) | 89 (12.9) | 2.120 (1.556-2.888) | < 0.001 | ||
| Fibrosis | Non-cirrhosis | 781 (28.6) | 252 (36.4) | < 0.001 | Reference | |
| Cirrhosis | 1946 (71.4) | 440 (63.6) | 0.685 (0.571-0.822) | < 0.001 | ||
‡, Black or African American; *, Includes American Indian/Alaska native, Asian, and Asian/Pacific Islander; #, Includes widowed, never married, divorced, separated, unmarried, and domestic partner; AFP: alpha fetoprotein; OR: odds ratio; CI: confidence interval.