Table 1.
Patient demographic and clinical characteristics
Factors | All (n=880)a | Nonsarcopenic (n=713)a | Sarcopenic (n=167)a | P |
---|---|---|---|---|
Age, mean (SD), years | 64.47 (10.80) | 62.35 (10.35) | 73.54 (7.50) | <0.001* |
Gender | 0.645 | |||
Female | 230 | 184 | 46 | |
Male | 650 | 529 | 121 | |
BMI, mean (SD), kg/m2 | 22.63 (3.07) | 22.91 (3.04) | 21.48 (2.96) | <0.001* |
NRS-2002 scores | <0.001* | |||
< 3 | 570 | 496 | 74 | |
≥ 3 | 310 | 217 | 93 | |
MUST scores | <0.001* | |||
< 1 | 487 | 419 | 68 | |
≥ 1 | 393 | 294 | 99 | |
MST scores | 0.003* | |||
< 2 | 617 | 516 | 101 | |
≥ 2 | 263 | 197 | 66 | |
SNAQ scores | 0.005* | |||
< 2 | 701 | 581 | 120 | |
≥ 2 | 179 | 132 | 47 | |
L3 SMI, mean (SD), cm2/m2 | 42.73 (7.74) | 43.86 (7.60) | 37.89 (6.41) | <0.001* |
Muscle attenuation,mean (SD), HU | 36.12 (7.81) | 37.43 (7.39) | 30.54 (7.10) | <0.001* |
Handgrip strength,mean (SD), kg | 28.40 (9.22) | 30.84 (8.21) | 18.11 (5.25) | <0.001* |
Gait speed,median (IQR), m/s | 1.00 (0.27) | 1.03 (0.25) | 0.81 (0.28) | <0.001* |
Albumin, mean (SD), g/L | 38.11 (4.45) | 38.71 (4.16) | 35.51 (4.74) | <0.001* |
Hemoglobin,mean (SD), g/L | 120.97 (21.61) | 123.52 (21.16) | 110.08 (20.15) | <0.001* |
ASA grade | <0.001* | |||
I | 208 | 183 | 25 | |
II | 522 | 426 | 96 | |
III | 150 | 104 | 46 | |
Charlson comorbidity index | 0.088 | |||
0 | 622 | 513 | 109 | |
1 | 174 | 139 | 35 | |
≥ 2 | 84 | 61 | 23 | |
Previous abdominal surgery | 0.145 | |||
No | 777 | 635 | 142 | |
Yes | 103 | 78 | 25 | |
Tumor location | 0.579 | |||
Not at cardia | 765 | 622 | 143 | |
At cardia | 115 | 91 | 24 | |
Differentiation of tumor | 0.505 | |||
Well differentiated | 304 | 250 | 54 | |
Poorly differentiated | 576 | 463 | 113 | |
TNM stage | 0.001* | |||
I | 310 | 272 | 38 | |
II | 214 | 167 | 47 | |
III | 356 | 274 | 82 | |
Extent of lymph node dissection | 0.219 | |||
D1 | 115 | 98 | 17 | |
D2 | 765 | 615 | 150 | |
Type of resection | 0.103 | |||
Subtotal gastrectomy | 549 | 454 | 95 | |
Total gastrectomy | 331 | 259 | 72 | |
Combined resection | 0.069 | |||
No | 810 | 662 | 148 | |
Yes | 70 | 51 | 19 | |
Laparoscopy-assisted surgery | 0.001* | |||
No | 644 | 504 | 140 | |
Yes | 236 | 209 | 27 |
a:Values are number of patients unless indicated otherwise;
*Statistically significant;
SD, standard deviation; BMI, body mass index; L3 SMI, third lumbar vertebra skeletal muscle index; IQR, interquartile range; ASA, American Society of Anesthesiologists; TNM, tumor-node-metastasis.