Table 1.
CDCA family member expression associated with clinical parameters (binary logistic regression)
| Clinical parameters | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| NUF2 | CDCA2 | CDCA3 | CDCA4 | ||||||
| Odds ratio | p-value | Odds ratio | p-value | Odds ratio | p-value | Odds ratio | p-value | ||
| Stage | II vs I | 2.374 (1.277-4.414) | 0.006* | 1.669 (0.841-3.310) | 0.143 | 1.732 (0.958-3.132) | 0.069 | 2.342 (1.282-4.279) | 0.006* |
| III vs I | 1.699 (1.120-2.577) | 0.013* | 1.416 (0.896-2.237) | 0.136 | 1.802 (1.188-2.732) | 0.006* | 1.720 (1.136-2.602) | 0.010* | |
| IV vs I | 1.943 (0.891-4.237) | 0.095 | 1.968 (0.779-4.969) | 0.152 | 1.930 (0.901-4.134) | 0.09 | 2.473 (1.132-5.399) | 0.023* | |
| Histologic grade | Moderate vs well | 1.727 (0.941-3.171) | 0.078 | 1.696 (0.989-2.908) | 0.055 | 1.785 (0.910-3.502) | 0.092 | 2.079 (1.109-3.897) | 0.022* |
| Poor vs well | 7.038 (4.151-11.932) | 0.000* | 4.436 (2.745-7.169) | 0.000* | 6.054 (3.395-10.795) | 0.000* | 5.927 (3.428-10.245) | 0.000* | |
| Poor vs moderate | 4.075 (2.613-6.355) | 0.000* | 2.616 (1.661-4.121) | 0.000* | 3.391 (2.134-5.390) | 0.000* | 2.851 (1.838-4.423) | 0.000* | |
| Histologic subtype | SEA vs EEA | 3.696 (2.323-5.883) | 0.000* | 1.407 (0.879-2.251) | 0.154 | 2.432 (1.593-3.713) | 0.000* | 2.533 (1.647-3.895) | 0.000* |
| CDCA5 | CBX2 | CDCA7 | CDCA8 | ||||||
| Odds ratio | p-value | Odds ratio | p-value | Odds ratio | p-value | Odds ratio | p-value | ||
| Stage | II vs I | 2.023 (1.055-3.882) | 0.034* | 1.363 (0.726-2.558) | 0.336 | 1.009 (0.535-1.902) | 0.978 | 1.876 (1.034-3.401) | 0.038* |
| III vs I | 2.399 (1.509-3.814) | 0.000* | 1.721 (1.115-2.656) | 0.014* | 0.934 (0.602-1.448) | 0.759 | 2.325 (1.528-3.537) | 0.000* | |
| IV vs I | 6.635 (1.970-22.346) | 0.000* | 1.038 (0.444-2.427) | 0.931 | 0.755 (0.344-1.653) | 0.482 | 2.989 (1.379-6.478) | 0.006* | |
| Histologic grade | Moderate vs well | 1.815 (1.023-3.220) | 0.042* | 1.418 (0.711-2.825) | 0.321 | 0.931 (0.503-1.723) | 0.82 | 2.602 (1.152-5.879) | 0.021* |
| Poor vs well | 13.806 (8.100-23.530) | 0.000* | 3.080 (1.723-5.506) | 0.000* | 0.554 (0.332-0.925) | 0.024* | 11.974 (5.831-24.589) | 0.000* | |
| Poor vs moderate | 7.607 (4.757-12.166) | 0.000* | 2.173 (1.333-3.543) | 0.002* | 0.595 (0.373-0.949) | 0.029* | 4.601 (2.814-7.524) | 0.000* | |
| Histologic subtype | SEA vs EEA | 18.167 (7.259-45.467) | 0.000* | 1.783 (1.154-2.755) | 0.009* | 0.349 (0.227-0.535) | 0.000* | 5.003 (3.196-7.830) | 0.000* |