Table 2.
Key regulated transcription factors and miRNA targets of CDCAs (Networkanalyst)
| Key TF | Description | Regulated gene |
|---|---|---|
| MXI1 | MAX Interactor 1 | CDCD4, CDCA7 |
| TFAP2C | Transcription Factor AP-2 Gamma | CDCA4, CDCA7 |
| E2F2 | E2F Transcription Factor 2 | CDCA3, CDCA7 |
| E2F1 | E2F Transcription Factor 1 | CDCA3, CDCA5, CDCA7 |
| SP1 | Sp1 Transcription Factor | CDCA2, CDCA3, CDCA5 |
| NFYA | Nuclear Transcription Factor Y Subunit Alpha | CDCA2, CDCA3, CDCA4 |
| TFAP2A | Transcription Factor AP-2 Alpha | CDCA4, CDCA5, CBX2, CDCA7 |
| MAX | MYC Associated Factor X | CDCA4, CDCA8 |
| EBF1 | EBF Transcription Factor 1 | CDCA4, CDCA8 |
| GABPA | GA Binding Protein Transcription Factor Subunit Alpha | NUF2, CDCA5 |
| EGR1 | Early Growth Response 1 | CDCA4, CBX2 |
| Key miRNA | Description | Regulated gene |
| hsa-miR-30b | - | CBX2, CDCA7 |
| hsa-miR-124 | - | CBX2, CDCA7 |
| hsa-miR-30a | - | CBX2, CDCA7 |