Table IV.
Correlations between serum levels of IL-34, IFN-α and IFN-λ1 and lupus nephritis (LN), SLE activity and response to therapy
| Patients | IL-34 Mean ±SD |
p | IFN-α Mean ±SD |
p | IFN-λ1 Mean ±SD |
p |
|---|---|---|---|---|---|---|
| With LN (n = 21) Without LN (n = 61) |
242 ±125.5 153.1 ±118.7 |
≤ 0.05 | 122.7 ±34.5 104.7 ±30.8 |
≤ 0.05 | 323.2 ±158.2 125.3 ±16 |
≤ 0.05 |
| With SLAM > 6 (n = 32) With SLAM ≤ 6 (n = 50) |
213.5±144.1 151.8±107.5 |
≤ 0.05 | 117.4 ±30.8 104.1 ±32.9 |
0.07 | 268.3 ±158.5 202 ±130.5 |
≤ 0.05 |
| With SLEDAI > 6 (n = 22) With SLEDAI ≤ 6 (n = 60) |
237.1 ±141.6 153.4 ±112.4 |
≤ 0.05 | 111.7 ±36.9 108.4 ±31.1 |
0.6 | 285.7 ±159.9 206.7 ±134.1 |
≤ 0.05 |
| With poor response (n = 27) With good response (n = 55) |
220.3 ±146.6 154.1 ±109.4 |
≤ 0.05 | 121.8 ±33 103.2 ±30 |
≤ 0.05 | 268.4 ±152.1 208.07 ±138.2 |
0.07 |