Supplemental Figure S1.

Ethnicity and exome capture kit assessment through the analysis of 2432 exome sequencing (ES) data sets. A: Total run of homozygosity (ROH) size distribution of the whole data set, classified by ES capture kits. B: Total ROH size distribution of the whole data set, according to different ethnicities reported. Dotted red lines indicate the defined consanguinity thresholds (22, 79, and 123 megabases). C, consanguineous; NC, nonconsanguineous; PC, probably consanguineous; U, uncertain; unknown, no consanguinity stated in the clinical record.