Table 3.

Distribution of biomarkers in pregnant participants with or without diabetes/endocrine disorders

Variables	Trimester of pregnancy	Healthy participants					Participants with type 1 diabetes only					Participants with type 2 diabetes only					Participants with gestational diabetes only					Participants with dyslipidemia only
		n = 32,136 (1st), 43,899 (2nd)					n = 28 (1st), 15 (2nd)					n = 35 (1st), 43 (2nd)					n = 1,002 (1st), 1,313 (2nd)					n = 149 (1st), 205 (2nd)
		2.5th	25th	50th	75th	97.5th	2.5th	25th	50th	75th	97.5th	2.5th	25th	50th	75th	97.5th	2.5th	25th	50th	75th	97.5th	2.5th	25th	50th	75th	97.5th
Adjusted HbA1c* (%)	First	4.7	5.0	5.2	5.4	5.7	5.2	5.9	6.4	7.0	9.1	5.0	5.6	6.0	6.7	10.7	4.8	5.2	5.4	5.6	6.4	4.7	5.1	5.2	5.5	5.9
	Second	4.6	5.0	5.1	5.4	5.7	5.2	5.6	6.1	6.7	7.7	4.8	5.4	6.0	6.4	7.6	4.7	5.1	5.4	5.6	6.2	4.6	5.1	5.2	5.5	5.8
TC (mg/dL)	First	135	168	188	210	261	122	170	183	210	257	142	166	184	202	234	145	174	195	217	263	158	204	225	251	328
	Second	145	181	203	227	279	164	172	191	214	231	149	182	198	223	289	148	184	206	230	289	172	224	245	278	362
LDL‐C (mg/dL)	First	58	84	99	117	158	50	75	93	104	142	61	84	95	124	145	64	89	107	124	166	83	113	124	156	232
	Second	64	92	109	128	174	68	90	91	117	148	57	95	105	128	176	66	96	112	132	181	79	126	144	174	261
HDL‐C (mg/dL)	First	51	66	74	83	103	56	68	78	99	123	33	57	64	73	107	49	63	73	83	101	48	65	75	84	108
	Second	53	69	77	87	107	48	68	72	84	102	43	59	66	81	91	50	66	75	85	104	52	71	80	91	116
TG (mg/dL)	First	53	86	111	146	253	45	73	91	126	232	44	112	151	196	295	63	97	127	169	321	64	108	144	200	383
	Second	61	98	125	163	280	46	79	124	180	281	72	123	159	232	434	65	108	142	190	332	72	114	143	195	329

^*Adjusted glycated hemoglobin (HbA1c) is defined as HbA1c (National Glycohemoglobin Standardization Program) or calculated HbA1c = 1.02 × HbA1c (Japan Diabetes Society) + 0.25. HDL‐C, high‐density lipoprotein cholesterol; LDL‐C, low‐density lipoprotein cholesterol; TC, total cholesterol; TG, triglyceride.