Table 2.
Rates of HR-HPV and other pathogens coinfections and risk of the coinfections in high-grade cervical lesions.
| Coinfection status | Overall | ≤LSIL | ≥HSIL | P valuea | P valueb | OR (95% CI) | ORadjust (95% CI) | P adjust | |
|---|---|---|---|---|---|---|---|---|---|
| HR-HPV (+) | PB (−) | 297 | 113 (38.0) | 184 (62.0) | 0.001∗ | 0.001∗ | 1 | 1 | 0.001∗ |
| PB (+) | 163 | 35 (21.5) | 128 (78.5) | 2.246 (1.445–3.491) | 2.250 (1.423–3.557) | ||||
| HR-HPV (−) | PB (−) | 355 | 337 (94.9) | 18 (5.1) | 0.024∗ | 1 | 1 | 0.023∗ | |
| PB (+) | 67 | 58 (86.6) | 9 (13.4) | 2.905 (1.245–6.779) | 2.779 (1.154–6.689) | ||||
| HR-HPV (+) | UU (−) | 335 | 118 (35.2) | 217 (65.8) | 0.022∗ | 0.001∗ | 1 | 1 | 0.020∗ |
| UU (+) | 125 | 30 (24.0) | 95 (76.0) | 1.722 (1.079–2.749) | 1.791 (1.096–2.926) | ||||
| HR-HPV (−) | UU (−) | 386 | 365 (94.6) | 21 (5.4) | 0.020∗ | 1 | 1 | 0.021∗ | |
| UU (+) | 36 | 30 (83.3) | 6 (6.7) | 3.476 (1.304–9.269) | 4.163 (1.243–13.941) | ||||
| HR-HPV (+) | MH (−) | 429 | 143 (14.5) | 286 (85.5) | 0.048∗ | 0.829 | 1 | 1 | 0.202 |
| MH (+) | 31 | 5 (35.7) | 26 (64.3) | 2.600 (0.978–6.913) | 1.930 (0.703–5.298) | ||||
| HR-HPV (−) | MH (−) | 392 | 368 (93.9) | 24 (6.1) | 0.427 | 1 | 1 | 0.461 | |
| MH (+) | 30 | 27 (90.0) | 3 (10.0) | 1.704 (0.482–6.020) | 0.551 (0.113–2.683) | ||||
| HR-HPV (+) | CT (−) | 384 | 137 (35.7) | 247 (64.3) | 0.001∗ | 0.001∗ | 1 | 1 | 0.001∗ |
| CT (+) | 76 | 11 (14.5) | 65 (85.5) | 3.278 (1.673–6.419) | 3.070 (1.540–6.120) | ||||
| HR-HPV (−) | CT (−) | 404 | 380 (94.1) | 24 (5.9) | 0.100 | 1 | 1 | 0.096 | |
| CT (+) | 18 | 15 (83.3) | 3 (6.7) | 3.167 (0.857–11.694) | 3.190 (0.815–12.494) | ||||
Values are presented as number (%). aCompared in different lower genital tract pathogens infection states. bCompared in different HR-HPV infection states. adjust: after adjustment for age and menopausal status. ∗P < 0.05. ≤LSIL: normal or low-grade squamous intraepithelial lesion; ≥HSIL: high-grade squamous intraepithelial lesion or cervical squamous cell carcinoma; HR-HPV: high-risk human papillomavirus; OR: odds ratio.