Table 2.
Infectious Toxicities (Grade ≥3)
| Patient ID | Decitabine Dose Level 1 | Toxicity Name | CTCAE v4.0 Grade | Organism |
|---|---|---|---|---|
| 138 | 15mg/m2 | Sepsis | 4 | Candida Lusitaniae |
| 141 | 15mg/m2 | Infections -other | 3 | Coagulase negative Staphylococus |
| Infections -other | 3 | Enterococcus Faecalis | ||
| Infections -other | 5 | Candida Kruseii | ||
| 146 | 15mg/m2 | Infections -other | 3 | Candida Kruseii |
| 147 | 15mg/m2 | Infections -other | 3 | Enterococcus |
| 149 | 15mg/m2 | Infections -other | 3 | Candida Kruseii |
| Patient ID | Decitabine Dose Level 2 | Toxicity Name | CTCAE v4.0 Grade | Organism |
| 182 | 10mg/m2 | Lip infection | 3 | Herpes Simplex Virus |
| 191 | 10mg/m2 | Infections -other | 3 | Klebsiella pneumonae |
| Enterocolitis | 3 | Clostridium difficile | ||
| sepsis | 4 | Candida guillermondi | ||
| 250 | 10mg/m2 | Enterocolitis | 3 | Adenovirus |
| Soft tissue infection | 3 | Pseudomonas aeruginosa | ||
| sepsis | 4 | Pseudomonas aeruginosa | ||
| 261 | 10mg/m2 | Lung infection | 3 | No organism isolated |
| Soft tissue infection | 4 | No organism isolated | ||
| Sepsis | 5 | Soft tissue infection | ||
| 268 | 10mg/m2 | Lung infection | 3 | No organism isolated |
| 269 | 10mg/m2 | Catheter related | 3 | Clostridium tertium |
| 284 | 10mg/m2 | Lung infection | 3 | Epstein-bar Virus |
| Sepsis | 4 | Rothia mucilaginosa; Streptococcus viridans | ||
| 285 | 10mg/m2 | Infections -other | 4 | Candida parapsilosis |
| Sepsis | 4 | Pseudomonas aeruginosa | ||
| 292 | 10mg/m2 | Catheter related | 3 | Staphylococcus capitis |
| Lung infection | 5 | No organism isolated | ||
| 299 | 10mg/m2 | Infections -other | 4 | Pseudomonas aeruginosa |
| Infections -other | 5 | Necrotizing fasciitis | ||
| 300 | 10mg/m2 | Infections -other | 5 | Bipolaris spicifera |
| 301 | 10mg/m2 | Lung infection | 5 | Fusarium |