Skip to main content
. Author manuscript; available in PMC: 2021 Mar 13.
Published in final edited form as: ACS Infect Dis. 2020 Jan 13;6(3):467–478. doi: 10.1021/acsinfecdis.9b00406

Figure 1. Pathways of interest probed in the antimetabolite screen.

Figure 1.

Products of folate and cysteine biosynthesis pathways feed into folate and methyl cycles. Pathway representations are simplified. RSAP = Reductive sulfate assimilation pathway; DHFR = Dihydrofolate reductase; SMX=Sulfamethoxazole; TMP = Trimethoprim; THF = Tetrahydrofolate; HCY = Homocysteine; SAM = S-adenosylmethionine.